Screening of metabolites produced by strains of Ganoderma Lucidum[curt.:fr] p.karst and Ganoderma Applanatum [pirs.:waller] pat. for their activity against tobacco mosaic vir
The higher Basidiomycetes mushrooms are impotent source of functional products which are widely used in folk medicine. During the study of mushrooms and produces of its metabolisms were found that they have antitumor, immunomodulating, antimicrobial andantiviral properties. But antiphitoviral activities have not been studied. The aim of our investigation was screening of Basidiomycetes species that can produce effective substances to plant pathogenic viruses. We investigated two species of the genus Ganoderma, specifically G.lucidum and G. applanatum As result of experiments we selected two most active strains, which could inhibit the viral infection to 65-70% at the concentration 1000 ?g/ml. The obtained results show that preparations have the highmolecular nature and can activate the plants protective mechanisms and block the virus penetration in the plant cell.